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AI models can also incorporate pharmacokinetic and pharmacodynamic parameters to predict nanoparticle absorption, distribution, metabolism, and excretion (ADME), helping identify potential toxicities early in development [232]

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Inflammasome activation, macrophage infiltration, and cytokine production have been documented in cystinosis, indicating that chronic inflammation plays a key role in disease pathogenesis [147]

Both tGSH ( P = 0.0055) and GSSG ( P = 0.0071) concentrations and the GSSG/GSH ratio ( P = 0.0227) correlated positively with disease duration until the first visit

Rarely, people may experience allergic reactions